Description
Nobiletin is a flavonoid extracted from citrus peels. It is an O-methylated flavone with the ability to reverse bulbectomy-induced memory impairment. Nobiletin has also been shown to affect circadian rhythms via their enhancement, resulting in protection against metabolic syndrome.
Nobiletin is a flavonoid compound found predominantly in citrus fruits, particularly in the peels of oranges and tangerines. This bioactive compound has gained significant interest due to its wide range of potential health benefits. Here’s an overview of the main benefits and applications of Nobiletin:
- Antioxidant Properties: Nobiletin is known for its strong antioxidant activity. Antioxidants are crucial for neutralizing harmful free radicals in the body, which can damage cells and lead to chronic diseases.
- Anti-inflammatory Effects: It exhibits anti-inflammatory properties, which can be beneficial in reducing inflammation-related conditions, such as arthritis and other inflammatory disorders.
- Neuroprotective Effects: Nobiletin has shown promise in protecting brain cells and potentially improving cognitive functions. This makes it a compound of interest in the study of neurodegenerative diseases like Alzheimer’s and Parkinson’s.
- Cardiovascular Health: Some studies suggest that Nobiletin may improve cardiovascular health by reducing cholesterol levels and preventing the buildup of plaque in the arteries, thus reducing the risk of heart disease.
- Anti-cancer Potential: Preliminary research indicates that Nobiletin may have anti-cancer properties, as it can inhibit the growth of cancer cells in various types of cancers. However, more research is needed in this area.
- Metabolic Benefits: It has been observed to have positive effects on metabolism, potentially aiding in the management of obesity and diabetes by improving insulin sensitivity and reducing blood sugar levels.
- Skin Health: Due to its antioxidant properties, Nobiletin is also used in skincare products to protect the skin from damage caused by UV rays and environmental pollutants.
- Food and Beverage Industry: In the food and beverage industry, Nobiletin is used as a natural flavoring agent and is valued for its citrusy aroma and flavor.
- Dietary Supplements: It is also available in dietary supplement form, often marketed for its health-promoting properties.
