Icariin

Product Name: Icariin
CAS No: 489-32-7
Synonyms: 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
MF: C33H40O15
MW: 676.66
Purity: 98% HPLC
CatLog: FS-HE-R005
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Description

Icariin is a type of flavonoid that is categorized as a prenylated flavonol glycoside. It is a kaempferol 3,7-O-diglucoside 8-prenyl compound. The compound was isolated from several varieties of plant in the genus Epimedium, also known as Horny Goat Weed or Yin Yang Huo. These plants’ extracts are said to have aphrodisiac properties and are used in traditional Chinese medicine to improve erectile performance.

Because of its widespread distribution and movement throughout the body, including the brain, icariin has a wide range of biological activities, including antioxidant and anti-inflammatory effects, neuroprotection, anti-tumor activity, and promoting overall health in the heart, bones, and a variety of other organs.

Benefits of Icariin:

  1. Enhancement of Sexual Health: Icariin is best known for its properties that may enhance sexual function. It is believed to work by increasing nitric oxide levels, which relaxes smooth muscle and allows for better blood flow, potentially improving erectile function.
  2. Bone Health Support: Some studies suggest that icariin may promote bone health, especially in postmenopausal women, by aiding in the preservation of bone mass.
  3. Neuroprotective Effects: There is evidence to suggest that icariin may have neuroprotective properties, potentially beneficial in neurodegenerative diseases like Alzheimer’s.
  4. Cardiovascular Health: Icariin may contribute to cardiovascular health by improving blood flow and reducing arterial stiffness.
  5. Anti-Inflammatory and Antioxidant: Like many flavonoids, icariin possesses anti-inflammatory and antioxidant properties, which can contribute to overall health and may protect against certain chronic diseases.

Applications and Main Usage:

  1. Supplements for Sexual Health: Icariin is widely used in supplements aimed at enhancing sexual performance and treating erectile dysfunction.
  2. Bone Health Supplements: Its potential role in bone density improvement makes it a candidate for inclusion in supplements targeting bone health, especially for postmenopausal women.
  3. Traditional Medicine: In traditional Chinese medicine, Epimedium, containing icariin, has been used for centuries for various health issues, including sexual dysfunction and fatigue.
  4. Research Tool: Icariin is also used in scientific research, particularly in studies related to sexual health, aging, and neurodegenerative diseases.