Apigenin

Product Name: Apigetrin
CAS No: 520-36-5
Synonyms: apigenin 7-O-beta-glucoside; apigenin-7-D-glucoside; apigenin-7-O-beta-D-glucopyranoside; cosmetin
MF: C15H10O5
MW: 270.24
Purity: 98% HPLC
CatLog: FS-HE-R016
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Description

Apigenin is a natural bioactive flavonoid compound found in a wide variety of plant sources. Chemically, it’s identified as 4′,5,7-trihydroxyflavone, and its molecular formula is C₁₅H₁₀O₅. This compound gives certain flowers and vegetables their vibrant colors.

Sources: Apigenin is primarily found in:

  • Parsley
  • Celery
  • Chamomile
  • Oranges
  • Grapefruits
  • Onions
  • Wheat sprouts
  • Tea (especially chamomile tea)

Applications:

  1. Dietary Supplements: Given its potential health benefits, apigenin is often included in dietary supplements.
  2. Cosmetic Products: Due to its anti-inflammatory, antioxidant, and anti-cancer properties, apigenin is used in skincare and cosmetic products.
  3. Research Tool: Scientists use apigenin in research, particularly in cancer research, to study its impact on cell signaling and its potential anti-tumor effects.

Benefits:

  1. Anti-inflammatory Effects: Apigenin has shown potential in reducing inflammation by inhibiting the production of certain pro-inflammatory cytokines.
  2. Antioxidant Activity: Like many flavonoids, apigenin is a potent antioxidant that can protect cells from damage by free radicals.
  3. Anti-cancer Properties: Some studies suggest that apigenin can inhibit cancer cell growth and proliferation. It has shown potential anti-cancer effects against several types of cancers including breast, digestive tract, skin, prostate, and blood cancers.
  4. Neuroprotective Effects: Research indicates that apigenin may support brain health and counteract neuroinflammatory conditions. Some studies also hint at its potential in reducing the risk of neurodegenerative diseases like Alzheimer’s.
  5. Anti-anxiety Effects: A study in mice has suggested that apigenin can produce mild anti-anxiety and mild sedative effects, which could be why chamomile tea, rich in apigenin, is often touted for its relaxing properties.
  6. Beneficial for Cardiovascular Health: Apigenin may support heart health by improving blood vessel function and reducing the risk of atherosclerosis.
  7. Supports Immune System: Some studies indicate that apigenin can modulate the immune response, potentially benefiting conditions like autoimmune diseases.