Troxerutin

Product Name  Troxerutin
CAS No.  7085-55-4
Molecular Formula  C33H42O19
Molecular Weight  742.69
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Description

Troxerutin, also known as vitamin P4, is a flavonoid that occurs naturally in tea, coffee, cereal grains, and vegetables. It possesses a variety of beneficial pharmacological and therapeutic properties, such as antioxidant, anti-inflammatory, anti-diabetic, and anti-tumor properties. Troxerutin has been used in clinical trials to treat Chronic Venous Insufficiency.

Troxerutin is a flavonoid derivative of the natural bioflavonoid rutin. It is commonly used in the treatment of various vascular conditions due to its beneficial properties. Here are the main benefits and applications of Troxerutin:

  1. Venous Health: Troxerutin is widely used for improving venous health. It strengthens the walls of veins, which helps in reducing the symptoms of chronic venous insufficiency, such as swelling, pain, and leg ulcers.
  2. Antioxidant Properties: As an antioxidant, Troxerutin neutralizes free radicals in the body, which helps to protect cells from damage. This antioxidant effect contributes to its therapeutic uses in vascular disorders.
  3. Anti-inflammatory Effects: Troxerutin exhibits anti-inflammatory properties, making it useful in reducing inflammation in conditions like phlebitis (inflammation of the veins) and hemorrhoids.
  4. Circulatory Improvement: By improving capillary permeability and reducing capillary fragility, Troxerutin enhances blood flow, especially in the microcirculation. This is beneficial for conditions where blood circulation needs to be improved.
  5. Eye Health: It is sometimes used to treat retinopathy, a condition affecting the retina of the eyes, especially in diabetic patients, due to its effects on microcirculation and capillary integrity.
  6. Reduction of Edema: Troxerutin can help reduce edema (swelling) in the legs, often associated with varicose veins or other circulatory problems.
  7. Radiation Protection: In some cases, Troxerutin has been used to protect the skin during radiation therapy, as it can help mitigate radiation-induced skin damage.

Applications of Troxerutin include:

  • Oral Supplements: It is often administered orally in capsule or tablet form for treating vascular disorders.
  • Topical Creams and Gels: Troxerutin is available in topical formulations for local application, especially for varicose veins and hemorrhoids.
  • Combination Therapy: It may be used in combination with other drugs or supplements to enhance the treatment of circulatory disorders.