Formononetin

Product Name  Formononetin
Synonyms  7-hydroxy-3-(4-methoxyphenyl)-4h-benzopyran-4-one
CAS  485-72-3
MF  C16H12O4
MW  268.27
Inquiry

Description

Formononetin is a phytoestrogen molecule found in plants such as red clover, kudzu, and soybeans. It has been researched for potential health advantages such as hormone balancing, bone health, and cardiovascular health.

Formononetin is well-known for its potential to behave as a selective estrogen receptor modulator (SERM), which means it may attach to estrogen receptors in the body and have either estrogenic or antiestrogenic effects depending on the tissue. This can assist to balance hormone levels in the body, which can help with problems like menopausal symptoms and osteoporosis.

Formononetin has also been discovered to have anticancer effects. It has been proven to decrease cancer cell development and induce apoptosis (programmed cell death) in several cancers, including breast, prostate, and colon cancer.

It’s recognized for its estrogen-like properties, which make it an interesting subject in research related to hormonal balance and menopause.

Main Benefits of Formononetin:

  1. Menopausal Symptom Relief: Formononetin has phytoestrogenic properties, meaning it can mimic the effects of estrogen in the body. This makes it potentially useful for alleviating symptoms of menopause, such as hot flashes and osteoporosis.
  2. Antioxidant Properties: Like many plant-derived compounds, formononetin has antioxidant capabilities, helping to neutralize harmful free radicals in the body.
  3. Anti-inflammatory Effects: It may also exert anti-inflammatory effects, which can be beneficial in reducing the risk of various chronic diseases.
  4. Potential Anti-Cancer Properties: Some studies have suggested that formononetin might have anti-tumor properties, particularly in hormone-related cancers like breast cancer, although more research is needed in this area.
  5. Cardiovascular Health: Its impact on lipid metabolism and atherosclerosis suggests it may be beneficial for heart health.

Applications of Formononetin:

  1. Dietary Supplements: Formononetin is often included in supplements, especially those targeted towards menopausal women for hormone balance and bone health.
  2. Research Tool: In scientific research, it is used to study estrogenic activity and its effects on various biological systems.
  3. Cosmetic Industry: Due to its antioxidant properties, formononetin is sometimes included in skin care products.
  4. Pharmaceutical Development: Its potential health benefits make it a candidate for the development of new pharmaceutical drugs, particularly in the area of hormone-related conditions and cancer.