6-Gingerol

Product Name  6-Gingerol
Synonyms  (5s)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)decan-3-one
CAS  23513-14-6
MF  C17H26O4
MW  294.39
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Description

6-Gingerol is the active constituent of fresh ginger, a spice commonly used in many cultures around the world for its flavor and health benefits. Chemically, it is classified as a phenolic compound and is related to other gingerols found in ginger, with slight variations in its structure.

Function

In the ginger root, 6-gingerol serves as a natural defense molecule with antimicrobial properties, helping protect the plant from pathogens and pests. For humans, it is best known for its pharmacological properties, including anti-inflammatory, antioxidant, anti-tumor, and antiemetic effects.

Applications and Benefits

1. Digestive Health:

  • Anti-nausea and Antiemetic Effects: 6-Gingerol is well-known for its ability to alleviate nausea and vomiting. It is particularly effective in treating morning sickness during pregnancy, motion sickness, and sometimes the nausea related to chemotherapy.

2. Anti-Inflammatory and Analgesic:

  • Pain Relief: Its anti-inflammatory properties make it a natural pain reliever. It’s often used by people suffering from arthritis or muscle soreness to reduce pain and improve mobility.

3. Antioxidant Properties:

  • Cellular Protection: As an antioxidant, 6-gingerol can neutralize harmful free radicals, potentially reducing the risk of chronic diseases and helping to protect against age-related damage.

4. Anticancer Potential:

  • Growth Inhibition: Several studies suggest that 6-gingerol may have anticancer properties, inhibiting the growth and survival of cancer cells, particularly in the digestive tract.

5. Cardiovascular Health:

  • Blood Thinner: 6-Gingerol may have a blood-thinning effect, potentially reducing the risk of blood clots. However, this also means it should be used with caution if combined with other blood thinners.
  • Cholesterol Management: There is evidence to suggest that 6-gingerol can help lower high cholesterol levels, which are a risk factor for heart disease.

6. Antimicrobial Activity:

  • Infection Prevention: It has been shown to possess antibacterial and antifungal properties, potentially helping to prevent or treat infections.